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Die sichtbarsten Arbeiten der Medizinischen Fakultät 2019, JIF > 20

Bauer, A1, Klemm, M1, Rizas, KD1, Hamm, W1, von Stülpnagel, L1, Dommasch, M, Steger, A, Lubinski, A, Flevari, P, ..., EU-CERT-ICD Investigators
Prediction of mortality benefit based on periodic repolarisation dynamics in patients undergoing prophylactic implantation of a defibrillator: a prospective, controlled, multicentre cohort study.
Lancet 2019; 394: 1344-1351 (JIF2017 59,1)
1 Medizinische Klinik und Poliklinik I

Renkawitz, J1, Kopf, A, Stopp, J, de Vries, I, Driscoll, MK, Merrin, J, Hauschild, R, Welf, ES, Danuser, G, ..., Sixt, M
Nuclear positioning facilitates amoeboid migration along the path of least resistance.
Nature 2019; 568: 546-550 (JIF2017 43,1)
1 Institut für Chirurgische Forschung

Guan, S1, Munder, A, Hedtfeld, S, Braubach, P, Glage, S, Zhang, L1, Lienenklaus, S, Schultze, A1, Hasenpusch, G, ..., Rosenecker, J1
Self-assembled peptide-poloxamine nanoparticles enable in vitro and in vivo genome restoration for cystic fibrosis.
Nat Nanotechnol 2019; 14: 287-297 (JIF2017 33,4)
1 Kinderklinik und Kinderpoliklinik im Dr. von Hauner'schen Kinderspital

Yin, C1, Ackermann, S, Ma, Z1, Mohanta, SK1, Zhang, C1, Li, Y1, Nietzsche, S, Westermann, M, Peng, L, ..., Habenicht, AJR1
ApoE attenuates unresolvable inflammation by complex formation with activated C1q.
Nat Med 2019; 25: 496-506 (JIF2017 30,6)
1 Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten

Klopstock, T1, Tricta, F, Neumayr, L, Karin, I1, Zorzi, G, Fradette, C, Kmiec, T, Büchner, B1, Steele, HE, ..., Vichinsky, E
Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study.
Lancet Neurol 2019; 18: 631-642 (JIF2017 28,8)
1 Neurologische Klinik und Poliklinik

Modest, DP1, Fischer von Weikersthal, L, Decker, T, Vehling-Kaiser, U, Uhlig, J, Schenk, M, Freiberg-Richter, J, Peuser, B, Denzlinger, C, ..., XELAVIRI/AIO KRK0110 Investigators,
Sequential Versus Combination Therapy of Metastatic Colorectal Cancer Using Fluoropyrimidines, Irinotecan, and Bevacizumab: A Randomized, Controlled Study-XELAVIRI (AIO KRK0110).
J Clin Oncol 2019; 37: 22-32 (JIF2017 28,2)
1 Medizinische Klinik und Poliklinik III

Aradi, D, Gross, L1, Trenk, D, Geisler, T, Merkely, B, Kiss, RG, Komócsi, A, Dézsi, CA, Ruzsa, Z, ..., Sibbing, D1
Platelet reactivity and clinical outcomes in acute coronary syndrome patients treated with prasugrel and clopidogrel: a pre-specified exploratory analysis from the TROPICAL-ACS trial.
Eur Heart J 2019; 40: 1942-1951 (JIF2017 23,2)
1 Medizinische Klinik und Poliklinik I

Seijkens, TTP1, Poels, K, Meiler, S, van Tiel, CM, Kusters, PJH, Reiche, M, Atzler, D1, Winkels, H, Tjwa, M, ..., Lutgens, E1
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death.
Eur Heart J 2019; 40: 372-382 (JIF2017 23,2)
1 Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten

de Juan, A1, Ince, LM1, Pick, R1, Chen, CS1, Molica, F, Zuchtriegel, G1, Wang, C, Zhang, D, Druzd, D1, ..., Scheiermann, C1
Artery-Associated Sympathetic Innervation Drives Rhythmic Vascular Inflammation of Arteries and Veins.
Circulation 2019; 140: 1100-1114 (JIF2017 23,1)
1 Institut für Chirurgische Forschung

Eze, C1, Käsmann, L1, Manapov, F1
Redefining the Role of Prophylactic Cranial Irradiation in the Modern Era of Active Surveillance in Small Cell Lung Cancer.
JAMA Oncol 2019; 5: 11-12 (JIF2017 22,4)
1 Klinik und Poliklinik für Strahlentherapie und Radioonkologie

Adrover, JM, Del Fresno, C, Crainiciuc, G, Cuartero, MI, Casanova-Acebes, M, Weiss, LA, Huerga-Encabo, H, Silvestre-Roig, C1, Rossaint, J, ..., Hidalgo, A1
A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.
Immunity 2019; 50: 390-402.e10 (JIF2017 21,5)
1 Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten