Die sichtbarsten Arbeiten der Medizinischen Fakultät 2015, JIF > 20

Willem M¹, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, ..., Haass C¹
η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Nature 2015; 526: 443-7 (JIF2014 41,5)
¹ Adolf-Butenandt-Institut

Barbosa JS, Sanchez-Gonzalez R, Di Giaimo R, Baumgart EV, Theis FJ, Götz M¹, Ninkovic J¹
Neurodevelopment. Live imaging of adult neural stem cell behavior in the intact and injured zebrafish brain.
Science 2015; 348: 789-93 (JIF2014 33,6)
¹ Physiologisches Institut, Lehrstuhl für Physiologische Genomik

Grünewald TG¹, Bernard V, Gilardi-Hebenstreit P, Raynal V, Surdez D, Aynaud MM, Mirabeau O, Cidre-Aranaz F, Tirode F, ..., Delattre O
Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite.
Nat Genet 2015; 47: 1073-8 (JIF2014 29,4)
¹ Pathologisches Institut

Reincke M¹, Sbiera S, Hayakawa A, Theodoropoulou M, Osswald A¹, Beuschlein F¹, Meitinger T, Mizuno-Yamasaki E, Kawaguchi K, ..., Komada M
Mutations in the deubiquitinase gene USP8 cause Cushing’s disease.
Nat Genet 2015; 47: 31-8 (JIF2014 29,4)
¹ Medizinische Klinik und Poliklinik IV

Kohl S¹, Zobor D, Chiang WC, Weisschuh N, Staller J, Gonzalez Menendez I, Chang S, Beck SC, Garcia Garrido M, ..., Lin JH¹
Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia.
Nat Genet 2015; 47: 757-65 (JIF2014 29,4)
1 Augenklinik und Poliklinik

Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M1, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, ..., Senderek J¹
Transcriptional regulator PRDM12 is essential for human pain perception.
Nat Genet 2015; 47: 803-8 (JIF2014 29,4)
1 Neurologische Klinik und Poliklinik

Bachhuber T¹, Katzmarski N, McCarter JF¹, Loreth D, Tahirovic S, Kamp F¹, Abou-Ajram C¹, Nuscher B¹, Serrano-Pozo A, ..., Meyer-Luehmann M¹
Inhibition of amyloid-β plaque formation by α-synuclein.
Nat Med 2015; 21: 802-7 (JIF2014 28,2)
¹ Adolf-Butenandt-Institut

Pastore A, Jurinovic V¹, Kridel R, Hoster E¹, Staiger AM, Szczepanowski M, Pott C, Kopp N, Murakami M, ..., Weigert O²
Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective clinical trial and validation in a population-based registry.
Lancet Oncol 2015; 16: 1111-22 (JIF2014 24,7)
¹ Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie
² Medizinische Klinik und Poliklinik III

Masserdotti G¹, Gillotin S, Sutor B¹, Drechsel D, Irmler M, Jørgensen HF, Sass S, Theis FJ, Beckers J, ..., Götz M¹
Transcriptional mechanisms of proneural factors and REST in regulating neuronal reprogramming of astrocytes.
Cell Stem Cell 2015; 17: 74-88 (JIF2014 22,3)
¹ Physiologisches Institut, Lehrstuhl für Physiologische Genomik

Hu D, Mohanta SK¹, Yin C¹, Peng L, Ma Z, Srikakulapu P, Grassia G, MacRitchie N, Dever G, ..., Habenicht AJ¹
Artery tertiary lymphoid organs control aorta immunity and protect against atherosclerosis via vascular smooth muscle cell lymphotoxin β receptors.
Immunity 2015; 42: 1100-15 (JIF2014 21,6)
¹ Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten

Yamano T¹, Nedjic J¹, Hinterberger M¹, Steinert M¹, Koser S, Pinto S, Gerdes N², Lutgens E², Ishimaru N, ..., Klein L¹
Intrathymic licensing of immigrating peripheral B cells for central T cell tolerance induction.
Immunity 2015; 42: 1048-1061 (JIF2014 21,6)
¹ Institut für Immunologie
² Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten